Understanding Vitamin D Deficiency (2024)

Vitamin D is often referred to as the "sunshine vitamin" because it is produced by your body when your skin is exposed to the sun. Since vitamin D helps to keep your bones strong, a deficiency can lead to bone softening and subsequent bone pain and fractures.

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What Does Vitamin D Have to Do With MS?

While vitamin D deficiency is unfortunately very common, the good news is that this health condition can be diagnosed with a simple blood test and treated with supplements.

Vitamin D Deficiency Symptoms

Most people with vitamin D deficiency are asymptomatic. Only with a severe and prolonged deficiency do symptoms arise.

The major role of vitamin D is to absorb calcium and phosphorus from the intestines in order to build and maintain bone mass. With vitamin D deficiency, this cannot occur adequately. With a severe deficiency, bone softening (a condition called osteomalacia in adults and rickets in children) may develop.

With osteomalacia and rickets, a person may experience throbbing bone discomfort and muscle weakness and pain. Osteomalacia also increases a person's chances of developing bone fractures, falling, and experiencing walking problems.

Besides bone and muscle symptoms, fatigue and depression are also associated with vitamin D deficiency.

Causes

Since you need sun exposure to make vitamin D, the most at-risk populations for vitamin D deficiency include anyone who spends a lot of time indoors (the elderly and the homebound, for example) and people with dark skin (as it produces less vitamin D from sunlight exposure).

Other populations at risk for vitamin D deficiency include:

  • Those who do not consume enough vitamin D-containing foods (e.g., canned tuna and fortified cow's milk)
  • Those with diseases that affect the absorption of vitamin D in the gut (e.g., celiac disease and Crohn's disease)
  • Those with diseases that affect the metabolism of vitamin D into its active form (e.g., chronic kidney disease or liver disease)
  • Those who are obese (extra fat tissue hides away vitamin D instead of releasing it into the bloodstream)
  • Those who take medications that enhance the breakdown of vitamin D (e.g., anti-seizure medications)

Interesting Associations

Besides its primary function in calcium metabolism, vitamin D may play a role in reducing inflammation and moderating immune function in the body. This may be why research has found links between vitamin D deficiency and various autoimmune diseases like multiple sclerosis, rheumatoid arthritis, and type 1 diabetes.

Understanding Vitamin D Deficiency (1)

Diagnosis

If you have one or more risk factors for vitamin D deficiency—for example, if you are obese, or if you have chronic kidney disease or a gut malabsorption syndrome—your healthcare provider should screen you for vitamin D deficiency.

Certain symptoms may also prompt your healthcare provider to test for vitamin D deficiency, such as an increased number of falls, especially if you are elderly.

However, screening for vitamin D deficiency in a person without symptoms is currently not recommended.

A simple blood test called 25-hydroxyvitamin D or 25(OH)D can be used to diagnose vitamin D deficiency.

While there is no definitive consensus about what a normal, healthy vitamin D level is, the Institute of Medicine (IOM) defines it as follows:

  • Normal: 25 (OH)D level greater than 20 ng/mL
  • Insufficient: 25 (OH)D level between 12 to 20 ng/mL
  • Deficient: 25 (OH)D level less than 12 ng/mL
  • High enough to cause adverse effects: 25 (OH)D greater than 50 ng/mL

Best At-Home Vitamin Deficiency Tests

Treatment

The treatment of vitamin D deficiency depends on a number of factors, such as the severity of the deficiency and whether certain underlying health problems exist.

That said, in the vast majority of cases, vitamin D deficiency is treated with a supplement.

Supplements

There are two major forms of vitamin D: vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol), the latter of which is used in most supplements.

To date, there is no standard regimen for treating vitamin D deficiency. A typical plan, though, may include taking 50,000 international units (IU) of vitamin D2 or D3 by mouth once a week for eight weeks, or 6,000 IU daily followed by a maintenance dose of 1,500 to 2,000 IU of vitamin D3 daily.

Keep in mind that higher doses will be needed to treat people with medical conditions that affect vitamin D absorption in the gut, and those taking medications that affect vitamin D metabolism.

Vitamin D Toxicity

Excess vitamin D may cause symptoms related to high calcium levels in the blood, such as muscle weakness, pain, heart arrhythmias, and kidney stones. This is why it is important to only take a vitamin D supplement as directed by your healthcare provider.

Food

Diet is an additional, although not robust, source of vitamin D, and therefore not usually recommended for treating a deficiency. That said, it can be useful for maintaining a healthy vitamin D level.

Foods that contain vitamin D include:

  • Fatty fish (e.g., salmon and swordfish)
  • Cod liver oil
  • Nuts
  • Cereals and dairy products fortified with vitamin D
  • Cheese
  • Eggs
  • Mushrooms
  • Beef liver

Sunlight

Sunlight is the third source of vitamin D. As with diet, it is not usually recommended as a treatment for vitamin D deficiency. This is because of the increased risk ofskin cancer associated with sun exposure.

Prevention

While the amount of vitamin D that a person needs varies based on factors like skin color and sun exposure, general recommendations from the IOM state that individuals ages 1 to 70 should take a supplement containing 600 IU of vitamin D daily. After age 70, a person should take 800 IU of vitamin D daily.

These vitamin D preventive recommendations are for the general population—not for people with a diagnosed vitamin D deficiency. People who are deficient in vitamin D require therapeutic doses of vitamin D.

In addition to or in lieu of taking a supplement, your healthcare provider may recommend that you eat or drink foods that contain vitamin D and/or that you get some sunshine (but not too much).

Is a Vitamin D Deficiency Behind Your IBS?

A Word From Verywell

The treatment of vitamin D deficiency is important for keeping your bones strong, and it may improve the health of other systems and tissues in your body like your immune system and heart.

However, before you make big changes, please talk with your healthcare provider first to decide what the best treatment plan is for you.

13 Sources

Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.

  1. Nadeem SB, Munim TF, Hussain HF, Hussain DF. Determinants of Vitamin D deficiency in asymptomatic healthy young medical students.Pak J Med Sci. 2018;34(5). doi:10.12669/pjms.345.15668

  2. Institute of Medicine (US) Committee to Review Dietary Reference Intakes for Vitamin D and Calcium; Ross AC, Taylor CL, Yaktine AL, et al., editors.Dietary Reference Intakes for Calcium and Vitamin D. Washington (DC): National Academies Press (US).

  3. Cleveland Clinic. Osteomalacia.

  4. Roy S, Sherman A, Monari-Sparks MJ, Schweiker O, Hunter K. Correction of low vitamin D improves fatigue: Effect of correction of low Vitamin D in fatigue study (EViDiF study). N Am J Med Sci. 2014 Aug;6(8):396-402. doi:10.4103/1947-2714.139291

  5. Wong SK, Chin KY, Ima-Nirwana S. Vitamin D and depression: The evidence from an indirect clue to treatment strategy. Curr Drug Targets. 2018;19(8):888-97. doi:10.2174/1389450118666170913161030

  6. Nair R, Maseeh A. Vitamin D: The "sunshine" vitamin. J Pharmacol Pharmacother. 2012;3(2):118-26. doi:10.4103/0976-500X.95506

  7. National Institutes of Health. Office of Dietary Supplements. Vitamin D fact sheet for health professionals.

  8. Cleveland Clinic. Vitamin D deficiency.

  9. Harrison SR, Li D, Jeffery LE, Raza K, Hewison M. Vitamin D, autoimmune disease and rheumatoid arthritis.Calcif Tissue Int. 2020;106(1):58-75. doi:10.1007/s00223-019-00577-2

  10. Holick MF, Binkley NC, Bischoff-Ferrari HA, et al. Evaluation, treatment, and prevention of vitamin D deficiency: an endocrine society clinical practice guideline.J Clin Endocrinol Metab. 2011;96(7):1911-1930. doi:10.1210/jc.2011-0385

  11. US Preventive Services Task Force, Krist AH, Davidson KW, et al. Screening for vitamin D deficiency in adults: US Preventive Services Task Force Recommendation Statement.JAMA. 2021;325(14):1436. doi:10.1001/jama.2021.3069

  12. Ross AC et al. The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: what clinicians need to know. J Clin Endocrinol Metab. 2011 Jan;96(1):53-8. doi:10.1210/jc.2010-2704

  13. Pilz S, Zittermann A, Trummer C, et al. Vitamin D testing and treatment: a narrative review of current evidence. Endocr Connect. 2019;8(2):R27-R43. doi:10.1530/EC-18-0432

By Mark Stibich, PhD
Mark Stibich, PhD, FIDSA, is a behavior change expert with experience helping individuals make lasting lifestyle improvements.

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Understanding Vitamin D Deficiency (2024)

FAQs

What are 3 things that happen if you are deficient in vitamin D? ›

Possible symptoms include:
  • Muscle pain.
  • Bone pain.
  • Increased sensitivity to pain.
  • A tingly, “pins-and-needles” sensation in the hands or feet.
  • Muscle weakness in body parts near the trunk of the body, such as the upper arms or thighs.
  • Waddling while walking, due to muscle weakness in the hips or legs.

How much vitamin D should I be taking if I have a vitamin D deficiency? ›

The amount of vitamin D you need to treat your deficiency depends on how deficient you are and your risk factors. Your doctor may start you on a higher dose of 6,000 IU of D3 a day. Once your level goes above 30 nanograms per milliliter, you will usually take a 1,000-2,000 IU supplement per day.

How long does it take to correct vitamin D deficiency? ›

Official answer. Generally, it takes a few weeks of taking daily vitamin D supplements for vitamin D levels in the body to rise. Each 1,000 IU of vitamin D3 taken daily is expected to raise blood levels of 25(OH)D by 10 ng/ml after a few weeks.

How do you feel when your vitamin D is low? ›

Symptoms when vitamin D is low

Most people with vitamin D deficiency are asymptomatic. However, if you're exhausted, your bones hurt, you have muscle weakness or mood changes, that's an indication that something may be abnormal with your body.

What blocks vitamin D absorption? ›

Medical conditions that can cause vitamin D deficiency

Cystic fibrosis, Crohn's disease and celiac disease: These conditions can prevent your intestines from adequately absorbing enough vitamin D through supplements, especially if the condition is untreated.

How to flush vitamin D out of system naturally? ›

Yes, by ensuring you consume plenty of water. This will encourage urination, allowing your body to shed the excess vitamin D and calcium more quickly. Prescription diuretics like furosemide can also be helpful. A diuretic is a medicine that increases fluid loss.

How to increase vitamin D levels quickly? ›

Here are three ways to increase your intake:
  1. Eat foods high in vitamin D, like fish or fortified breakfast foods (milk, cereals and orange juice).
  2. Get vitamin D from moderate sunlight exposure each day.
  3. Take a vitamin D3 supplement or cod liver oil.
Jul 19, 2022

What happens if your vitamin D is low for too long? ›

Vitamin D deficiency can lead to a loss of bone density, which can contribute to osteoporosis and fractures (broken bones). Severe vitamin D deficiency can also lead to other diseases: In children, it can cause rickets. Rickets is a rare disease that causes the bones to become soft and bend.

Does low vitamin D cause weight gain? ›

You're Experiencing Weight Gain

In fact, according to a Medical News Today article, an increase in overall body fat and low vitamin D seem to go hand in hand. If you're looking to lose weight, it's time to up your vitamin D intake, either through sun exposure and/or a high-quality supplement.

How to check vitamin D levels at home? ›

Everlywell is an online company that offers a variety of at-home test kits and ships within the United States. An Everlywell vitamin D test involves you taking a finger-prick blood sample. Results will show whether your vitamin D levels are elevated, adequate, or suboptimal.

Is it better to take vitamin D every day or once a week? ›

The recommended amount of vitamin D to take daily for adults aged 19–70 is 15 micrograms (mcg), or 600 IU. You can get vitamin D in food and supplements, and your body naturally makes vitamin D when you're exposed to the sun. Food sources include beef liver, cheese, and fatty fish.

What is the best form of vitamin D for absorption? ›

Vitamin D is best supplemented in the form of D3 (cholecalciferol) – the form produced by the skin in response to sunlight (UVB) exposure. This form must then be converted in the liver (to calcidiol) and then in the kidneys to its active form (calcitriol).

What are the 3 effects of vitamin D on the body? ›

Together with calcium, vitamin D also helps protect older adults from osteoporosis. Vitamin D has other roles in the body, including reduction of inflammation as well as modulation of such processes as cell growth, neuromuscular and immune function, and glucose metabolism [1-3].

Who does vitamin D deficiency affect the most? ›

For most adults, vitamin D deficiency is not a concern. However, some groups — particularly people who are obese, who have dark skin and who are older than age 65 — may have lower levels of vitamin D due to their diets, little sun exposure or other factors.

Does low vitamin D cause anxiety? ›

Recent Findings. Low vitamin D levels are associated with increased symptoms of depression and anxiety. For this reason, vitamin D screening should be performed in the prevention and treatment planning of these mood disorders.

Can low vitamin D cause neurological symptoms? ›

A deficiency of Vitamin D, B-12, or E is most strongly linked to neurological problems.

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